Solution‐Based Determination of Dissociation Constants for the Binding of Aβ42 to Antibodies
Abstract Amyloid β‐peptides (Aβ) play a major role in the pathogenesis of Alzheimer's disease. Therefore, numerous monoclonal antibodies against Aβ have been developed for basic and clinical research. The present study applied fluorescence based analytical ultracentrifugation and microscale the...
Main Authors: | Tao Zhang, Dr. Luitgard Nagel‐Steger, Prof. Dr. Dieter Willbold |
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Format: | Article |
Language: | English |
Published: |
Wiley-VCH
2019-07-01
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Series: | ChemistryOpen |
Subjects: | |
Online Access: | https://doi.org/10.1002/open.201900167 |
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