Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue.

At least four laboratories have shown that endogenous cardiac progenitor cells (CPCs) can be grown directly from adult heart tissue in primary culture, as cardiospheres or their progeny (cardiosphere-derived cells, CDCs). Indeed, CDCs are already being tested in a clinical trial for cardiac regenera...

Full description

Bibliographic Details
Main Authors: Darryl R Davis, Yiqiang Zhang, Rachel R Smith, Ke Cheng, John Terrovitis, Konstantinos Malliaras, Tao-Sheng Li, Anthony White, Raj Makkar, Eduardo Marbán
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2745677?pdf=render