Novel gene therapy viral vector using non-oncogenic lymphotropic herpesvirus.

Despite the use of retroviral vectors, efficiently introducing target genes into immunocytes such as T cells is difficult. In addition, retroviral vectors carry risks associated with the oncogenicity of the native virus and the potential for introducing malignancy in recipients due to genetic carryo...

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Bibliographic Details
Main Authors: Akihiro Shimizu, Nobuyuki Kobayashi, Kazuya Shimada, Kuniaki Oura, Tadao Tanaka, Aikou Okamoto, Kazuhiro Kondo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3569415?pdf=render