ChIP-Seq and RNA-Seq analyses identify components of the Wnt and Fgf signaling pathways as Prep1 target genes in mouse embryonic stem cells.

ChIP-Seq and RNA-Seq analyses identify components of the Wnt and Fgf signaling pathways as Prep1 target genes in mouse embryonic stem cells.

The Prep1 (Pknox1) homeodomain transcription factor is essential at multiple stages of embryo development. In the E11.5 embryo trunk, we previously estimated that Prep1 binds about 3,300 genomic sites at a highly specific decameric consensus sequence, mainly governing basal cellular functions. We no...

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Bibliographic Details
Main Authors: Audrey Laurent, Manuela Calabrese, Hans-Jörg Warnatz, Marie-Laure Yaspo, Vsevolod Tkachuk, Miguel Torres, Francesco Blasi, Dmitry Penkov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395233?pdf=render

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http://europepmc.org/articles/PMC4395233?pdf=render

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