ETV7 regulates breast cancer stem-like cell features by repressing IFN-response genes

Abstract Cancer stem cells (CSCs) represent a population of cells within the tumor able to drive tumorigenesis and known to be highly resistant to conventional chemotherapy and radiotherapy. In this work, we show a new role for ETV7, a transcriptional repressor member of the ETS family, in promoting...

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Bibliographic Details
Main Authors: Laura Pezzè, Erna Marija Meškytė, Mattia Forcato, Stefano Pontalti, Kalina Aleksandra Badowska, Dario Rizzotto, Ira-Ida Skvortsova, Silvio Bicciato, Yari Ciribilli
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04005-y