Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor.

Neurotrophins and their receptors control a number of cellular processes, such as survival, gene expression and axonal growth, by activating multiple signalling pathways in peripheral neurons. Whether each of these pathways controls a distinct developmental process remains unknown. Here we describe...

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Bibliographic Details
Main Authors: Svetlana Gorokhova, Stéphane Gaillard, Louise Urien, Pascale Malapert, Wassim Legha, Grégory Baronian, Jean-Pierre Desvignes, Serge Alonso, Aziz Moqrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3916231?pdf=render