T cell activation markers and African mitochondrial DNA haplogroups among non-Hispanic black participants in AIDS clinical trials group study 384.

T cell activation markers and African mitochondrial DNA haplogroups among non-Hispanic black participants in AIDS clinical trials group study 384.

Mitochondrial function influences T cell dynamics and is affected by mitochondrial DNA (mtDNA) variation. We previously reported an association between African mtDNA haplogroup L2 and less robust CD4 cell recovery on antiretroviral therapy (ART) in non-Hispanic black ACTG 384 subjects. We explored w...

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Bibliographic Details
Main Authors: Todd Hulgan, Gregory K Robbins, Spyros A Kalams, David C Samuels, Benjamin Grady, Robert Shafer, Deborah G Murdock, Doug Selph, David W Haas, Richard B Pollard, AIDS Clinical Trials Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3433792?pdf=render

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http://europepmc.org/articles/PMC3433792?pdf=render

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