Characterisation of the Trichinella spiralis deubiquitinating enzyme, TsUCH37, an evolutionarily conserved proteasome interaction partner.

Trichinella spiralis is a zoonotic parasitic nematode that causes trichinellosis, a disease that has been identified on all continents except Antarctica. During chronic infection, T. spiralis larvae infect skeletal myofibres, severely disrupting their differentiation state.An activity-based probe, H...

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Bibliographic Details
Main Authors: Rhiannon R White, Sachiko Miyata, Eliseo Papa, Eric Spooner, Kleoniki Gounaris, Murray E Selkirk, Katerina Artavanis-Tsakonas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3186758?pdf=render