Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice

<p>Abstract</p> <p>Background</p> <p>Pulmonary fibrosis is characterized by excessive deposition of extracellular matrix in the interstitium resulting in respiratory failure. The role of remodeling mediators such as metalloproteinases (MMPs) and their inhibitors (TIMPs)...

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Bibliographic Details
Main Authors: Boichot Elisabeth, Guenon Isabelle, Nenan Soazig, Manoury Boris, Planquois Jean-Michel, Bertrand Claude P, Lagente Vincent
Format: Article
Language:English
Published: BMC 2006-02-01
Series:Journal of Inflammation
Online Access:http://www.journal-inflammation.com/content/3/1/2