Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice
<p>Abstract</p> <p>Background</p> <p>Pulmonary fibrosis is characterized by excessive deposition of extracellular matrix in the interstitium resulting in respiratory failure. The role of remodeling mediators such as metalloproteinases (MMPs) and their inhibitors (TIMPs)...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-02-01
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Series: | Journal of Inflammation |
Online Access: | http://www.journal-inflammation.com/content/3/1/2 |