Bias Characterization in Probabilistic Genotype Data and Improved Signal Detection with Multiple Imputation.

Missing data are an unavoidable component of modern statistical genetics. Different array or sequencing technologies cover different single nucleotide polymorphisms (SNPs), leading to a complicated mosaic pattern of missingness where both individual genotypes and entire SNPs are sporadically absent....

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Bibliographic Details
Main Authors: Cameron Palmer, Itsik Pe'er
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4910998?pdf=render