Bias Characterization in Probabilistic Genotype Data and Improved Signal Detection with Multiple Imputation.
Missing data are an unavoidable component of modern statistical genetics. Different array or sequencing technologies cover different single nucleotide polymorphisms (SNPs), leading to a complicated mosaic pattern of missingness where both individual genotypes and entire SNPs are sporadically absent....
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-06-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4910998?pdf=render |