White matter differences between healthy young ApoE4 carriers and non-carriers identified with tractography and support vector machines.

White matter differences between healthy young ApoE4 carriers and non-carriers identified with tractography and support vector machines.

The apolipoprotein E4 (ApoE4) is an established risk factor for Alzheimer's disease (AD). Previous work has shown that this allele is associated with functional (fMRI) changes as well structural grey matter (GM) changes in healthy young, middle-aged and older subjects. Here, we assess the diffu...

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Bibliographic Details
Main Authors: Laurence O'Dwyer, Franck Lamberton, Silke Matura, Monika Scheibe, Julia Miller, Dan Rujescu, David Prvulovic, Harald Hampel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338494?pdf=render

Internet

http://europepmc.org/articles/PMC3338494?pdf=render

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