Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy

Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy

Abstract Germline alterations in the RB1 tumor suppressor gene predispose patients to develop retinoblastoma (RB) in both eyes. While similar treatment is given for each eye, there is often a variable therapeutic response between the eyes. Herein, we use the aqueous humor (AH) liquid biopsy to evalu...

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Bibliographic Details
Main Authors: Elyssa Y. Wong, Liya Xu, Lishuang Shen, Mary E. Kim, Ashley Polski, Rishvanth K. Prabakar, Rachana Shah, Rima Jubran, Jonathan W. Kim, Jaclyn A. Biegel, Xiaowu Gai, Peter Kuhn, James Hicks, Jesse L. Berry
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-021-00212-0

Internet

https://doi.org/10.1038/s41698-021-00212-0

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