Distinct Bioenergetic Features of Human Invariant Natural Killer T Cells Enable Retained Functions in Nutrient-Deprived States

Distinct Bioenergetic Features of Human Invariant Natural Killer T Cells Enable Retained Functions in Nutrient-Deprived States

Invariant natural killer T (iNKT) cells comprise a unique subset of lymphocytes that are primed for activation and possess innate NK-like functional features. Currently, iNKT cell-based immunotherapies remain in early clinical stages, and little is known about the ability of these cells to survive a...

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Bibliographic Details
Main Authors: Priya Khurana, Chakkapong Burudpakdee, Stephan A. Grupp, Ulf H. Beier, David M. Barrett, Hamid Bassiri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
immunometabolism
glycolysis
cytokine production and cytotoxicity
fatty acid oxidation (FAO)
human invariant natural killer T cells (iNKT) cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.700374/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.700374/full

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