Development of Novel High-Resolution Size-Guided Turbidimetry-Enabled Particle Purification Liquid Chromatography (PPLC): Extracellular Vesicles and Membraneless Condensates in Focus

Development of Novel High-Resolution Size-Guided Turbidimetry-Enabled Particle Purification Liquid Chromatography (PPLC): Extracellular Vesicles and Membraneless Condensates in Focus

Acellular particles (extracellular vesicles and membraneless condensates) have important research, drug discovery, and therapeutic implications. However, their isolation and retrieval have faced enormous challenges, impeding their use. Here, a novel size-guided particle purification liquid chromatog...

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Bibliographic Details
Main Authors: Hussein Kaddour, Yuan Lyu, Nadia Shouman, Mahesh Mohan, Chioma M. Okeoma
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular vesicles (EVs)
exosomes
membraneless condensates (MCs)
gradient size exclusion chromatography (gSEC)
UV-Vis spectroscopy
Online Access:https://www.mdpi.com/1422-0067/21/15/5361

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https://www.mdpi.com/1422-0067/21/15/5361

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