JNK pathway activation is controlled by Tao/TAOK3 to modulate ethanol sensitivity.

Neuronal signal transduction by the JNK MAP kinase pathway is altered by a broad array of stimuli including exposure to the widely abused drug ethanol, but the behavioral relevance and the regulation of JNK signaling is unclear. Here we demonstrate that JNK signaling functions downstream of the Ster...

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Bibliographic Details
Main Authors: David Kapfhamer, Ian King, Mimi E Zou, Jana P Lim, Ulrike Heberlein, Fred W Wolf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3515618?pdf=render