Dendritic Cell Migration Toward CCL21 Gradient Requires Functional Cx43

Dendritic Cell Migration Toward CCL21 Gradient Requires Functional Cx43

Dendritic cells (DCs) travel through lymphatic vessels to transport antigens and present them to T cells in lymph nodes. DCs move directionally toward lymphatics by virtue of their CCR7 and a CCL21 chemotactic gradient. We evaluated in vivo and in bone marrow-derived dendritic cells (BMDCs) whether...

Full description

Bibliographic Details
Main Authors: Richard Ruez, Juan Dubrot, Alice Zoso, Marc Bacchetta, Filippo Molica, Stéphanie Hugues, Brenda R. Kwak, Marc Chanson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Physiology
Subjects:
dendritic cells
connexins
migration
chemotaxis
mice
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00288/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00288/full

Similar Items