In Vitro Effects of Curcumin on Transforming Growth Factor-β-mediated Non-Smad Signaling Pathway, Oxidative Stress, and Pro‐inflammatory Cytokines Production with Human Vascular Smooth Muscle Cells

In Vitro Effects of Curcumin on Transforming Growth Factor-β-mediated Non-Smad Signaling Pathway, Oxidative Stress, and Pro‐inflammatory Cytokines Production with Human Vascular Smooth Muscle Cells

Transforming growth factor-β (TGF-β) induces pro-inflammatory cytokines expression including interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) and these cytokines are associated with the development of atherosclerosis. Curcumin has anti-atherogenic effects and anti-inflammatory propertie...

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Bibliographic Details
Main Authors: Amirhooman Asadi, Davood Yaghobi Nezhad, Amirreza Rafie Javazm, Parisa Khanicheragh, Ladan Mashouri, Fatemeh Shakeri, Mojtaba Abbasi, Mahya Sadat Afrazian, Zahra Niknam, Omid Abazari
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2020-02-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Curcumin
Interleukin-6
Smad2 protein
Transforming growth factor beta
Tumor necrosis factor-alpha
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2472

Internet

https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2472

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