Genetic alterations in Ki-ras and Ha-ras genes in Juvenile Nasopharyngeal Angiofibromas and head and neck cancer

CONETXT: Ras gene mutations have been associated to a wide range of human solid tumors. Members of the ras gene family (Ki-ras, Ha-ras and N-ras) are structurally related and code for a protein (p21) known to play an important role in the regulation of normal signal transduction and cell growth. The...

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Main Authors: Cláudia Malheiros Coutinho, Alessandra Simões Bassini, Leonardo Guilhermino Gutiérrez, Ossamu Butugan, Luiz Paulo Kowalski, Maria Mitzi Brentani, Maria Aparecida Nagai
Format: Article
Language:English
Published: Associação Paulista de Medicina 1999-05-01
Series:São Paulo Medical Journal
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801999000300004&lng=en&tlng=en