Development and initial evaluation of a novel method for assessing tissue-specific plasma free fatty acid utilization in vivo using (R)-2-bromopalmitate tracer

Development and initial evaluation of a novel method for assessing tissue-specific plasma free fatty acid utilization in vivo using (R)-2-bromopalmitate tracer

We describe a method for assessing tissue-specific plasma free fatty acid (FFA) utilization in vivo using a non-β-oxidizable FFA analog, [9,10-3H]-(R)-2-bromopalmitate (3H-R-BrP). Ideally 3H-R-BrP would be transported in plasma, taken up by tissues and activated by the enzyme acyl-CoA synthetase (AC...

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Bibliographic Details
Main Authors: Nicholas D. Oakes, Ann Kjellstedt, Gun-Britt Forsberg, Tony Clementz, Germán Camejo, Stuart M. Furler, Edward W. Kraegen, Maria Ölwegård-Halvarsson, Arthur B. Jenkins, Bengt Ljung
Format: Article
Language:English
Published: Elsevier 1999-06-01
Series:Journal of Lipid Research
Subjects:
metabolism
turnover
analog
muscle
liver
heart
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520335203

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http://www.sciencedirect.com/science/article/pii/S0022227520335203

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