Empagliflozin Protects HK-2 Cells from High Glucose-Mediated Injuries via a Mitochondrial Mechanism

Empagliflozin Protects HK-2 Cells from High Glucose-Mediated Injuries via a Mitochondrial Mechanism

Empagliflozin is known to retard the progression of kidney disease in diabetic patients. However, the underlying mechanism is incompletely understood. High glucose induces oxidative stress in renal tubules, eventually leading to mitochondrial damage. Here, we investigated whether empagliflozin exhib...

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Bibliographic Details
Main Authors: Wen-Chin Lee, You-Ying Chau, Hwee-Yeong Ng, Chiu-Hua Chen, Pei-Wen Wang, Chia-Wei Liou, Tsu-Kung Lin, Jin-Bor Chen
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
empagliflozin
mitochondria
proximal tubular cell
diabetic kidney disease
Online Access:https://www.mdpi.com/2073-4409/8/9/1085

Internet

https://www.mdpi.com/2073-4409/8/9/1085

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