CD4 T-cell responses in primary HIV infection: interrelationship with immune activation and virus burden

CD4 T-cell responses in primary HIV infection: interrelationship with immune activation and virus burden

Early events during primary HIV infection (PHI) are thought to influence disease outcome. Although a growing body of evidence suggests a beneficial role of HIV-specific CD4 help in HIV infection, it is unclear how early viral replication, systemic immune activation and antiretroviral therapy (ART) m...

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Bibliographic Details
Main Authors: Mathieu F. Chevalier, Céline Didier, Pierre-Marie Girard, Maria E Manea, Pauline Campa, Françoise Barré-Sinoussi, Daniel Scott-Algara, Laurence Weiss
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Immunology
Subjects:
Viral Load
HIV-specific CD4 T cells
antiretroviral therapy
acute HIV infection
generalized immune activation
early ART initiation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00395/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00395/full

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