Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41

<p>Abstract</p> <p>Background</p> <p>We previously described the construction of an HIV-1 envelope glycoprotein complex (Env) that is stabilized by an engineered intermolecular disulfide bond (SOS) between gp120 and gp41. The modified Env protein antigenically mimics th...

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Bibliographic Details
Main Authors: Caffrey Michael, Busser Els, Dankers Martijn M, Sanders Rogier W, Moore John P, Berkhout Ben
Format: Article
Language:English
Published: BMC 2004-03-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/1/1/3