Energy homeostasis in leptin deficient Lepob/ob mice.

Maintenance of reduced body weight is associated both with reduced energy expenditure per unit metabolic mass and increased hunger in mice and humans. Lowered circulating leptin concentration, due to decreased fat mass, provides a primary signal for this response. However, leptin deficient (Lepob/ob...

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Bibliographic Details
Main Authors: Alicja A Skowronski, Yann Ravussin, Rudolph L Leibel, Charles A LeDuc
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5738099?pdf=render