Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling

Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling

Glial activation and neuroinflammation play significant roles in apoptosis as well as in the development of cognitive and memory deficits. Neuroinflammation is also a critical feature in the pathogenesis of neurodegenerative disorders such as Alzheimer and Parkinson’s diseases. Previously,...

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Bibliographic Details
Main Authors: Tahir Muhammad, Muhammad Ikram, Rahat Ullah, Shafiq Ur Rehman, Myeong Ok Kim
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Nutrients
Subjects:
LPS
microglia/astrocytes
neuroinflammation
tumor necrosis factor (TNF)
reactive oxygen species (ROS)
neurodegeneration
memory Impairments
hesperetin
Online Access:http://www.mdpi.com/2072-6643/11/3/648

Internet

http://www.mdpi.com/2072-6643/11/3/648

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