HIF-1α as a Target Molecule in the Use of Triazino-Indole Derivative on the Acoustic Trauma Model

HIF-1α as a Target Molecule in the Use of Triazino-Indole Derivative on the Acoustic Trauma Model

The effect of triazino-indole derivative (Trisan) on hypoxia-inducible factor (HIF) expression level in the organ of Corti, when administering it for therapeutic and preventive purposes, was investigated using an acoustic trauma model in experimental animals (female F1 hybrids of CBA and C57BL/6 lin...

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Bibliographic Details
Main Authors: Vladimir L. Pastushenkov, Leonid G. Buynov, Maksim S. Kuznetsov, Vladimir V. Dvorianchikov, Lev A. Glaznikov, Aleksandr L. Pastushenkov
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Audiology Research
Subjects:
hypoxia
hypoxia-inducible factor
HIF-1α
acoustic trauma
antihypoxants
triazino-indole
Online Access:https://www.mdpi.com/2039-4349/11/3/34

Internet

https://www.mdpi.com/2039-4349/11/3/34

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