De novo synthesized estradiol protects against methylmercury-induced neurotoxicity in cultured rat hippocampal slices.

De novo synthesized estradiol protects against methylmercury-induced neurotoxicity in cultured rat hippocampal slices.

BACKGROUND: Estrogen, a class of female sex steroids, is neuroprotective. Estrogen is synthesized in specific areas of the brain. There is a possibility that the de novo synthesized estrogen exerts protective effect in brain, although direct evidence for the neuroprotective function of brain-synthes...

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Bibliographic Details
Main Authors: Takeshi Yamazaki, Megumi Yamamoto, Yasuhiro Ishihara, Shota Komatsu, Eiji Munetsuna, Masahiro Onizaki, Atsuhiko Ishida, Suguru Kawato, Takao Mukuda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3566000?pdf=render

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http://europepmc.org/articles/PMC3566000?pdf=render

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