Altered Cofactor Preference of Thermostable StDAPDH by a Single Mutation at K159

Altered Cofactor Preference of Thermostable StDAPDH by a Single Mutation at K159

D-amino acid production from 2-keto acid by reductive amination is an attractive pathway because of its high yield and environmental safety. StDAPDH, a <i>meso</i>-diaminopimelate dehydrogenase (<i>meso</i>-DAPDH) from <i>Symbiobacterium thermophilum</i>, was the...

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Bibliographic Details
Main Authors: Xiuzhen Gao, Qinyuan Ma, Huihui Song, Xinming Sun, Zhiyun Li, Mingfei Liu
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>meso</i>-diaminopimelate dehydrogenase
d-amino acid
thermostable enzyme
cofactor engineering
molecular dynamics simulations
Online Access:https://www.mdpi.com/1422-0067/21/5/1788

Internet

https://www.mdpi.com/1422-0067/21/5/1788

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