Distinctive Metabolomics Patterns Associated With Insulin Resistance and Type 2 Diabetes Mellitus

Distinctive Metabolomics Patterns Associated With Insulin Resistance and Type 2 Diabetes Mellitus

Obesity is associated with an increased risk of insulin resistance (IR) and type 2 diabetes mellitus (T2DM) which is a multi-factorial disease associated with a dysregulated metabolism and can be prevented in pre-diabetic individuals with impaired glucose tolerance. A metabolomic approach emphasizin...

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Bibliographic Details
Main Authors: Xinyun Gu, Mohammed Al Dubayee, Awad Alshahrani, Afshan Masood, Hicham Benabdelkamel, Mahmoud Zahra, Liang Li, Anas M. Abdel Rahman, Ahmad Aljada
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
type 2 diabetes mellitus
insulin resistance
obesity
untargeted metabolomics profiling
clinical metabolic panel
chemical isotope labeling liquid chromatography
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.609806/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2020.609806/full

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