MAGI1 Mediates eNOS Activation and NO Production in Endothelial Cells in Response to Fluid Shear Stress

MAGI1 Mediates eNOS Activation and NO Production in Endothelial Cells in Response to Fluid Shear Stress

Fluid shear stress stimulates endothelial nitric oxide synthase (eNOS) activation and nitric oxide (NO) production through multiple kinases, including protein kinase A (PKA), AMP-activated protein kinase (AMPK), AKT and Ca<sup>2+</sup>/calmodulin-dependent protein kinase II (CaMKII). Mem...

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Bibliographic Details
Main Authors: Kedar Ghimire, Jelena Zaric, Begoña Alday-Parejo, Jochen Seebach, Mélanie Bousquenaud, Jimmy Stalin, Grégory Bieler, Hans-Joachim Schnittler, Curzio Rüegg
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
fluid shear stress
MAGI1
signal transduction
eNOS
endothelial cell
nitric oxide/NO
Online Access:https://www.mdpi.com/2073-4409/8/5/388

Internet

https://www.mdpi.com/2073-4409/8/5/388

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