Age-Related Changes in the Behavior of Apolipoprotein E Knockout Mice

Age-Related Changes in the Behavior of Apolipoprotein E Knockout Mice

The knockout mouse model, B6.129P2-Apoetm1Unc is homozygotic for the Apolipoprotein E (ApoE) deletion; thus, it is capable of developing hyperlipidemia and atherosclerosis but ApoE is also a lipid-transport protein abundantly expressed in most neurons in the central nervous system, so these animals...

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Bibliographic Details
Main Authors: Dasha Fuentes, Nidia Fernández, Yenela García, Teidy García, Ana Ruth Morales, Roberto Menéndez
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Behavioral Sciences
Subjects:
aging
ApoE
behavior
mice
neurodegenerative disorder
Online Access:http://www.mdpi.com/2076-328X/8/3/33

Internet

http://www.mdpi.com/2076-328X/8/3/33

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