Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures.

Human motor neurons derived from embryonic and induced pluripotent stem cells (hESCs and hiPSCs) are a potentially important tool for studying motor neuron survival and pathological cell death. However, their basic survival requirements remain poorly characterized. Here, we sought to optimize a robu...

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Bibliographic Details
Main Authors: Nuno Jorge Lamas, Bethany Johnson-Kerner, Laurent Roybon, Yoon A Kim, Alejandro Garcia-Diaz, Hynek Wichterle, Christopher E Henderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4206291?pdf=render