Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research.

Induced pluripotent stem cell (iPSC) technology can be used to model human disorders, create cell-based models of human diseases, including neurodegenerative diseases, and in establishing therapeutic strategies. To detect subtle cellular abnormalities associated with common late-onset disease in iPS...

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Bibliographic Details
Main Authors: Takuya Yagi, Arifumi Kosakai, Daisuke Ito, Yohei Okada, Wado Akamatsu, Yoshihiro Nihei, Akira Nabetani, Fuyuki Ishikawa, Yasumichi Arai, Nobuyoshi Hirose, Hideyuki Okano, Norihiro Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22848530/pdf/?tool=EBI