Corticotropin-Releasing Factor: An Ancient Peptide Family Related to the Secretin Peptide Superfamily

Corticotropin-releasing factor (CRF) is the hypothalamic releasing peptide that regulates the hypothalamic-pituitary-adrenal/inter-renal (HPA/I) axis in vertebrates. Over the last 25 years, there has been considerable discussion on its paralogs genes, urotensin-I/urocortin-1, and urocortins-2 and-3...

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Bibliographic Details
Main Authors: Ola M. Michalec, Belinda S. W. Chang, Nathan R. Lovejoy, David A. Lovejoy
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00529/full