Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets

Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets

Abstract Background Liposarcoma, the most common soft tissue tumor, is understudied cancer, and limited progress has been made in the treatment of metastatic disease. The Achilles heel of cancer often is their kinases that are excellent therapeutic targets. However, very limited knowledge exists of...

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Bibliographic Details
Main Authors: Deepika Kanojia, Manoj Garg, Jacqueline Martinez, Anand M.T., Samuel B. Luty, Ngan B. Doan, Jonathan W. Said, Charles Forscher, Jeffrey W. Tyner, H. Phillip Koeffler
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Journal of Hematology & Oncology
Subjects:
Liposarcoma
Ponatinib
Kinase inhibitor
Therapeutics
Online Access:http://link.springer.com/article/10.1186/s13045-017-0540-x

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http://link.springer.com/article/10.1186/s13045-017-0540-x

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