Serum Exosomes Derived from Irritable Bowel Syndrome Patient Increase Cell Permeability via Regulating miR-148b-5p/RGS2 Signaling in Human Colonic Epithelium Cells

Aim. Irritable bowel syndrome (IBS) is a multifactorial functional bowel disorder characterized by disruption of the intestinal barrier. Circulating exosomal microRNAs (miRNAs) are involved in regulating epithelial barrier function, and upregulation of miR-148b-5p has been detected in IBS. However,...

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Bibliographic Details
Main Authors: Ying Xing, Shan Xue, Jing Wu, Jianhong Zhou, Fangfang Xing, Tianxing Li, Xiaohu Nie
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2021/6655900