High-throughput drug screening models of mature adipose tissues which replicate the physiology of patients’ Body Mass Index (BMI)

Obesity is a complex and incompletely understood disease, but current drug screening strategies mostly rely on immature in vitro adipose models which cannot recapitulate it properly. To address this issue, we developed a statistically validated high-throughput screening model by seeding human mature...

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Bibliographic Details
Main Authors: Fiona Louis, Yoshihiro Sowa, Shiro Kitano, Michiya Matsusaki
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-01-01
Series:Bioactive Materials
Subjects:
BMI
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21002401