Some outcomes and a hypothetical mechanism of combined lead and benzo(a)pyrene intoxication, and its alleviation with a complex of bioprotectors

Some outcomes and a hypothetical mechanism of combined lead and benzo(a)pyrene intoxication, and its alleviation with a complex of bioprotectors

Rats were exposed 3 times a week during 6 weeks to repeated intraperitoneal injections of lead acetate solution in water (Pb) and/or benzo(а)pyrene solution in petrolatum oil (B(а)P) in various dose ratios. Towards the end of the period, the animals developed a moderate subchronic intoxication havin...

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Bibliographic Details
Main Authors: Ilzira A. Minigalieva, Tatiana N. Shtin, Oleg H. Makeyev, Vladimir G. Panov, Larisa I. Privalova, Vladimir B. Gurvic, Marina P. Sutunkova, Tatiana V. Bushueva, Renata R. Sakhautdinova, Svetlana V. Klinova, Svetlana N. Solovyeva, Ivan N. Chernyshov, Eugene A. Shuman, Artem A. Korotkov, Boris A. Katsnelson
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Toxicology Reports
Subjects:
Benzo(a)pyrene
Lead
Biotransformation
Combined toxicity and genotoxicity
Bioprotectors
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750020303668

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http://www.sciencedirect.com/science/article/pii/S2214750020303668

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