Lafora disease E3-ubiquitin ligase malin is related to TRIM32 at both the phylogenetic and functional level
<p>Abstract</p> <p>Background</p> <p>Malin is an E3-ubiquitin ligase that is mutated in Lafora disease, a fatal form of progressive myoclonus epilepsy. In order to perform its function, malin forms a functional complex with laforin, a glucan phosphatase that facilitates...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-07-01
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Series: | BMC Evolutionary Biology |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2148/11/225 |