Bovine herpesvirus 4-based vector delivering the full length xCT DNA efficiently protects mice from mammary cancer metastases by targeting cancer stem cells

Bovine herpesvirus 4-based vector delivering the full length xCT DNA efficiently protects mice from mammary cancer metastases by targeting cancer stem cells

Despite marked advancements in its treatment, breast cancer is still the second leading cause of cancer death in women, due to relapses and distal metastases. Breast cancer stem cells (CSCs), are a cellular reservoir for recurrence, metastatic evolution and disease progression, making the developmen...

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Bibliographic Details
Main Authors: Gaetano Donofrio, Giulia Tebaldi, Stefania Lanzardo, Roberto Ruiu, Elisabetta Bolli, Andrea Ballatore, Valeria Rolih, Francesca Macchi, Laura Conti, Federica Cavallo
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:OncoImmunology
Subjects:
mammary cancer
cancer stem cell
xct
immunotherapy
bovine herpesvirus 4-based vector
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1494108

Internet

http://dx.doi.org/10.1080/2162402X.2018.1494108

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