The polymorphism rs6918289 located in the downstream region of the TREM2 gene is associated with TNF-α levels and IMT-F

Abstract Triggering receptor expressed on myeloid cells 2 (TREM2) is known for its anti-inflammatory properties during the immune response, and influences negatively on TNF-α expression levels. Genetic epidemiology studies have identified polymorphisms located in the TREM2 gene associated with neuro...

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Bibliographic Details
Main Authors: Vesna Gorenjak, Alex-Ander Aldasoro Arguinano, Sébastien Dadé, Maria G. Stathopoulou, Dwaine R. Vance, Christine Masson, Sophie Visvikis-Siest
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25553-y