BAFF Blockade Attenuates Inflammatory Responses and Intestinal Barrier Dysfunction in a Murine Endotoxemia Model

BAFF Blockade Attenuates Inflammatory Responses and Intestinal Barrier Dysfunction in a Murine Endotoxemia Model

B cell-activating factor (BAFF) production is increased in septic patients. However, the specific role of BAFF in sepsis remains unknown. This study was designed to investigate the expression and function of BAFF in an experimental endotoxemia model and to identify the potential mechanisms. We estab...

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Bibliographic Details
Main Authors: Runze Quan, Chaoyue Chen, Wei Yan, Ying Zhang, Xi Zhao, Yu Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
B cell activating factor
endotoxemia
inflammation
tight junction
intestinal mucosal barrier
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.570920/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.570920/full

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