Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets
Cells store energy in the form of neutral lipids (NLs) packaged into micrometer-sized organelles named lipid droplets (LDs). These structures emerge from the endoplasmic reticulum (ER) at sites marked by the protein seipin, but the mechanisms regulating their biogenesis remain poorly understood. Usi...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/62886 |