Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets

Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets

Cells store energy in the form of neutral lipids (NLs) packaged into micrometer-sized organelles named lipid droplets (LDs). These structures emerge from the endoplasmic reticulum (ER) at sites marked by the protein seipin, but the mechanisms regulating their biogenesis remain poorly understood. Usi...

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Bibliographic Details
Main Authors: Valeria Zoni, Rasha Khaddaj, Pablo Campomanes, Abdou Rachid Thiam, Roger Schneiter, Stefano Vanni
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
lipid membranes
lipid droplets
molecular dynamics
Online Access:https://elifesciences.org/articles/62886

Internet

https://elifesciences.org/articles/62886

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