Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism

Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism

Abstract Background Autism spectrum disorder (ASD) is a clinically and biologically heterogeneous condition characterized by social, repetitive, and sensory behavioral abnormalities. No treatments are approved for the core diagnostic symptoms of ASD. To enable the earliest stages of therapeutic disc...

Full description

Bibliographic Details
Main Authors: Sameer C. Dhamne, Jill L. Silverman, Chloe E. Super, Stephen H. T. Lammers, Mustafa Q. Hameed, Meera E. Modi, Nycole A. Copping, Michael C. Pride, Daniel G. Smith, Alexander Rotenberg, Jacqueline N. Crawley, Mustafa Sahin
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Molecular Autism
Subjects:
Shank3B
Pentylenetetrazol
Gamma oscillations
Repetitive behavior
Social behavior
Autism
Online Access:http://link.springer.com/article/10.1186/s13229-017-0142-z

Internet

http://link.springer.com/article/10.1186/s13229-017-0142-z

Similar Items