HER2 gene (ERBB2) amplification is a rare event in non-liver-fluke associated cholangiocarcinogenesis

HER2 gene (ERBB2) amplification is a rare event in non-liver-fluke associated cholangiocarcinogenesis

Abstract Background Cholangiocarcinoma is a rapidly fatal cancer entity with a median survival of less than one year. In contrast to many other malignancies, no substantial therapeutic breakthrough has been made in the past few decades, thereby limiting the treatment to cytotoxic chemotherapy with l...

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Bibliographic Details
Main Authors: Thomas Albrecht, Melina Rausch, Stephanie Rössler, Michael Albrecht, Jana Dorothea Braun, Veronika Geissler, Arianeb Mehrabi, Monika Nadja Vogel, Anita Pathil-Warth, Gunhild Mechtersheimer, Marcus Renner, Christian Rupp, Karl Heinz Weiss, Elena Busch, Bruno Köhler, Christoph Springfeld, Peter Schirmacher, Benjamin Goeppert
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Cancer
Subjects:
HER2
Biliary tract cancer
Cholangiocarcinoma
Targeted therapy
Predictive biomarkers
Online Access:https://doi.org/10.1186/s12885-019-6320-y

Internet

https://doi.org/10.1186/s12885-019-6320-y

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