Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending

Bacterial Xer site-specific recombinases play an essential genome maintenance role by unlinking chromosome multimers, but their mechanism of action has remained structurally uncharacterized. Here, we present two high-resolution structures of Helicobacter pylori XerH with its recombination site DNA d...

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Bibliographic Details
Main Authors: Aleksandra Bebel, Ezgi Karaca, Banushree Kumar, W Marshall Stark, Orsolya Barabas
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/19706