F-Spondin Is the Signal by Which 2-Methoxyestradiol Induces Apoptosis in the Endometrial Cancer Cell Line Ishikawa

F-Spondin Is the Signal by Which 2-Methoxyestradiol Induces Apoptosis in the Endometrial Cancer Cell Line Ishikawa

The metabolite 2-methoxyestradiol (2ME) is an endogenous estrogen metabolite with potential therapeutic properties in reproductive cancers. However, the molecular mechanisms by which 2ME exerts its anticancer activity are not well elucidated. The purpose of this study was to determine the molecular...

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Bibliographic Details
Main Authors: Ramiro Rincón-Rodriguez, Dennise Mena, Javier Mena, Patricia Díaz-Saldivar, Emanuel Guajardo-Correa, Carlos Godoy-Guzman, Hugo Cardenas, Pedro A. Orihuela
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
cancer
2-methoxyestradiol
F-spondin
Ishikawa cells
apoptosis
Online Access:https://www.mdpi.com/1422-0067/20/16/3850

Internet

https://www.mdpi.com/1422-0067/20/16/3850

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