5-ALA Fluorescence in Native Pituitary Adenoma Cell Lines: Resection Control and Basis for Photodynamic Therapy (PDT)?

OBJECTIVE:Pituitary adenomas (PA), especially invasive ones, are often not completely resectable. Usage of 5-aminolevulinic acid (5-ALA) for fluorescence guided surgery could improve the rate of total resection and, additionally, open the doors for photodynamic therapy (PDT) in case of unresectable...

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Bibliographic Details
Main Authors: Andrei Nemes, Thomas Fortmann, Stephan Poeschke, Burkhard Greve, Daniel Prevedello, Antonio Santacroce, Walter Stummer, Volker Senner, Christian Ewelt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5008746?pdf=render