Predictive markers of clinical outcome in the GRMD dog model of Duchenne muscular dystrophy

Predictive markers of clinical outcome in the GRMD dog model of Duchenne muscular dystrophy

In the translational process of developing innovative therapies for DMD (Duchenne muscular dystrophy), the last preclinical validation step is often carried out in the most relevant animal model of this human disease, namely the GRMD (Golden Retriever muscular dystrophy) dog. The disease in GRMD dog...

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Bibliographic Details
Main Authors: Inès Barthélémy, Fernanda Pinto-Mariz, Erica Yada, Loïc Desquilbet, Wilson Savino, Suse Dayse Silva-Barbosa, Anne-Marie Faussat, Vincent Mouly, Thomas Voit, Stéphane Blot, Gillian Butler-Browne
Format: Article
Language:English
Published: The Company of Biologists 2014-11-01
Series:Disease Models & Mechanisms
Subjects:
GRMD
DMD
Dystrophin
Dog
Predictive biomarker
Lymphocyte
CD49d
Gait analysis
Accelerometry
Online Access:http://dmm.biologists.org/content/7/11/1253

Internet

http://dmm.biologists.org/content/7/11/1253

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