Differential effects of 17α-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat

Differential effects of 17α-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat

Effects of 17α-ethinylestradiol (EE) on the neutral and acidic biosynthetic pathways of bile salt (BS) synthesis were evaluated in rats with an intact enterohepatic circulation and in rats with long-term bile diversion to induce BS synthesis. For this purpose, bile salt pool composition, synthesis o...

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Bibliographic Details
Main Authors: Nynke R. Koopen, Sabine M. Post, Henk Wolters, Rick Havinga, Frans Stellaard, Renze Boverhof, Folkert Kuipers, Hans M.G. Princen
Format: Article
Language:English
Published: Elsevier 1999-01-01
Series:Journal of Lipid Research
Subjects:
cholestasis
estrogens
bile
Δ22-β-muricholate
cholesterol-7α-hydroxylase
sterol-27-hydroxylase
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520333447

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http://www.sciencedirect.com/science/article/pii/S0022227520333447

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